A class can be declared as sealed. In that case, it is not possible to declare a descendent class. The compiler will return an error if it encounters a declaration of a descendent:
{$mode objfpc}
{$h+}
Type
  TMyClass = Class Sealed
    x : integer;
  end;
  TMyClass2 = Class(TMyClass)
    Y : Integer;
  end;
begin
end.
This will result in the following error:
Error: Cannot create a descendant of the sealed class "TMyClass"
An abstract class is a class that cannot be instantiated directly. Instead, a descendent class must always be instantiated. However, for Delphi compatibility, the compiler ignores this directive.